Pimobendan 74150-27-9 Metabolism PDE inhibitor
Isanwo:T/T, L/C
Ipilẹṣẹ ọja:China
Ibudo Gbigbe:Beijing/Shanghai/Hangzhou
Bere fun (MOQ):1g
Akoko asiwaju:3 ṣiṣẹ ọjọ
Agbara iṣelọpọ:1 kg / osù
Ipo ipamọ:Ti fipamọ ni itura, ibi gbigbẹ, iwọn otutu yara.
Ohun elo idii:vial, igo
Iwọn idii:1g/vial, 5/vial, 10g/vial, 50g/igo, 500g/igo
Alaye aabo:UN 2811 6.1/PG 3
Ọrọ Iṣaaju
Pimobendan, jẹ oogun ti ogbo.O jẹ sensitizer kalisiomu ati oludaniloju yiyan ti phosphodiesterase 3 (PDE3) pẹlu inotropic rere ati awọn ipa vasodilator.
Pimobendan ni a lo ninu iṣakoso ikuna ọkan ninu awọn aja, eyiti o wọpọ julọ nipasẹ arun falifu mitral myxomatous (ti a tun mọ tẹlẹ bi endocardiosis), tabi cardiomyopathy dilated.Iwadi ti fihan pe bi monotherapy kan, pimobendan mu akoko iwalaaye pọ si ati ilọsiwaju didara igbesi aye ni awọn alaisan aja pẹlu ikuna ọkan iṣọn-alọ ọkan ni atẹle si arun falifu mitral nigba akawe pẹlu benazepril, oludena ACE kan.
Ni pato (USP43)
| Nkan | Sipesifikesonu |
| Ifarahan | Funfun tabi die-die yellowish lulú, hygroscopic |
| Mp | Nipa 242 ℃ |
| Solubility | Ni iṣe ti ko ṣee ṣe ninu omi, tiotuka larọwọto ni dimethylformamide, tiotuka die-die ni acetone ati ni kẹmika. |
| Idanimọ | spectrophotometry gbigba infurarẹẹdi, Ifiwera pimobendan CRS. |
| Akoko idaduro ti tente oke pataki ti ojutu Ayẹwo ni ibamu si ti ojutu Ọja Standard, bi a ti gba ninu idanwo Awọn impurities Organic. | |
| Awọn irin ti o wuwo | ≤10ppm |
| Atokun | P90 ≤ 25μ m |
| Iwọn patiku | 20-80 apapo |
| Awọn olomi ti o ku | ≤500ppm |
| Omi | ≤ 1.0% |
| Ayẹwo | 98.0% ~ 102.0% |
| eeru sulfate | ≤ 0.10% |
| Awọn nkan ti o jọmọ (HPLC) | |
| aimọ́ A | ≤ 0.10% |
| aimọ́ B | ≤ 0.10% |
| Eyikeyi miiran aimọ | ≤ 0.10% |
| Lapapọ aimọ | ≤ 0.20% |
